Western blot analysis of extracts from COS7 cells treated with Etoposide using Phospho-CDC25B (Ser353) antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from COS7 cells treated with Etoposide using Phospho-CDC25B (Ser353) antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-CDC25B (Ser353) Antibody
CSB-PA570157
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetCDC25B
Overview
- SupplierCusabio
- Product NamePhospho-CDC25B (Ser353) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID994
- Target nameCDC25B
- Target descriptioncell division cycle 25B
- Target synonymsCDC25 homolog B; dual specificity phosphatase Cdc25B; M-phase inducer phosphatase 2
- HostRabbit
- IsotypeIgG
- Protein IDP30305
- Protein NameM-phase inducer phosphatase 2
- Scientific DescriptionCdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. Reboutier D, et al. (2012) J Cell Biol 197, 19-26 Lobjois V, et al. (2011) Biochem Biophys Res Commun 410, 87-90 Feng C, et al. (2007) Biol Reprod 77, 560-8
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203