Western blot analysis of extracts from HepG2 cells treated with Forskolin using Phospho-CDK1/CDC2 (Thr14) antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HepG2 cells treated with Forskolin using Phospho-CDK1/CDC2 (Thr14) antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-CDK2 (Thr14) Antibody
CSB-PA228346
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCDK2
Overview
- SupplierCusabio
- Product NamePhospho-CDK2 (Thr14) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1017
- Target nameCDK2
- Target descriptioncyclin dependent kinase 2
- Target synonymscdc2-related protein kinase; CDKN2; cell division protein kinase 2; cyclin-dependent kinase 2; p33 protein kinase; p33(CDK2)
- HostRabbit
- IsotypeIgG
- Protein IDP24941
- Protein NameCyclin-dependent kinase 2
- Scientific DescriptionSerine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1, B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Sarkar S, Dey BK, Dutta A (2010) Mol Biol Cell 21, 2138-49 Shreeram S, Hee WK, Bulavin DV (2008) Mol Cell Biol 28, 7442-50 Mayya V, et al. (2006) Mol Cell Proteomics 5, 1146-57
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203