Western blot analysis of extracts from Jurkat cells treated with PMA using Phospho-CHOP (Ser30) antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from Jurkat cells treated with PMA using Phospho-CHOP (Ser30) antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-DDIT3 (Ser30) Antibody
CSB-PA799326
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetDDIT3
Overview
- SupplierCusabio
- Product NamePhospho-DDIT3 (Ser30) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1649
- Target nameDDIT3
- Target descriptionDNA damage inducible transcript 3
- Target synonymsAltDDIT3; alternative DDIT3 protein; C/EBP zeta; c/EBP-homologous protein 10; C/EBPzeta; CCAAT/enhancer-binding protein homologous protein; CEBPZ; CHOP; CHOP10; CHOP-10; DNA damage-inducible transcript 3 protein; GADD153; growth arrest and DNA damage-inducible protein GADD153
- HostRabbit
- IsotypeIgG
- Protein IDP35638
- Protein NameDNA damage-inducible transcript 3 protein
- Scientific DescriptionMultifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Ubeda M, Habener JF (2003) J Biol Chem 278, 40514-20
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203