Immunohistochemical analysis of paraffin-embedded human prostate carcinoma tissue using PEK/PERK (Phospho-Thr982) antibody (left)or the same antibody preincubated with blocking peptide (right).
Immunohistochemical analysis of paraffin-embedded human prostate carcinoma tissue using PEK/PERK (Phospho-Thr982) antibody (left)or the same antibody preincubated with blocking peptide (right).
Phospho-EIF2AK3 (Thr981) Antibody
CSB-PA072558
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetEIF2AK3
Overview
- SupplierCusabio
- Product NamePhospho-EIF2AK3 (Thr981) Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9451
- Target nameEIF2AK3
- Target descriptioneukaryotic translation initiation factor 2 alpha kinase 3
- Target synonymseukaryotic translation initiation factor 2-alpha kinase 3; pancreatic EIF2-alpha kinase; PEK; PERK; PRKR-like endoplasmic reticulum kinase; truncated eukaryotic translation initiation factor 2 alpha kinase 3; WRS
- HostRabbit
- IsotypeIgG
- Protein IDQ9NZJ5
- Protein NameEukaryotic translation initiation factor 2-alpha kinase 3
- Scientific DescriptionPhosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1) Shi Y., An J., J. Biol. Chem. 274:5723-5730(1999). Sood R., Biochem. J. 346:281-293(2000). The MGC Project Team; Genome Res. 14:2121-2127(2004).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203