Western blot analysis of extracts from JK cells (Lane 2), using EPHA2/5 (Phospho-Tyr594) Antibody. The lane on the left is treated with antigen-specific peptide.
Western blot analysis of extracts from JK cells (Lane 2), using EPHA2/5 (Phospho-Tyr594) Antibody. The lane on the left is treated with antigen-specific peptide.
Phospho-EPHA2/EPHA5 (Tyr594) Antibody
CSB-PA584934
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetEPHA2
Overview
- SupplierCusabio
- Product NamePhospho-EPHA2/EPHA5 (Tyr594) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1969
- Target nameEPHA2
- Target descriptionEPH receptor A2
- Target synonymsARCC2; CTPA; CTPP1; CTRCT6; ECK; ephrin type-A receptor 2; epithelial cell receptor protein tyrosine kinase; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK
- HostRabbit
- IsotypeIgG
- Protein IDP29317
- Protein NameEphrin type-A receptor 2
- Scientific DescriptionReceptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. Lindberg R.A., Mol. Cell. Biol. 10:6316-6324(1990). Gregory S.G., Nature 441:315-321(2006).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203