
Western blot analysis of extracts from 293 cells untreated or treated with starvation using G3BP-1(Phospho-Ser232) Antibody.
Phospho-G3BP1 (Ser232) Antibody
CSB-PA908450
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetG3BP1
Overview
- SupplierCusabio
- Product NamePhospho-G3BP1 (Ser232) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10146
- Target nameG3BP1
- Target descriptionG3BP stress granule assembly factor 1
- Target synonymsATP-dependent DNA helicase VIII; DNA helicase VIII; G3BP; G3BP-1; GAP binding protein; GAP SH3 domain-binding protein 1; GTPase activating protein (SH3 domain) binding protein 1; HDH-VIII; ras GTPase-activating protein-binding protein 1; RasGAP-associated endoribonuclease G3BP; Ras-GTPase-activating protein SH3-domain-binding protein
- HostRabbit
- IsotypeIgG
- Protein IDQ13283
- Protein NameRas GTPase-activating protein-binding protein 1
- Scientific DescriptionMay be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3 tail or hanging tails at both 5- and 3-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5 to 3 direction along the bound single-stranded DNA. Tao WA, et al. (2005) Nat Methods. 2(8): 591-598. Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730. Beausoleil SA, et al. (2004) Proc Natl Acad Sci U S A.101 (33): 12130-12135. Tourrihre H, et al. (2003) J Cell Biol.160 (6): 823-831.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203