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Western Blot analysis of 293 cells using Phospho-GSK3 beta (Ser9) Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of 293 cells using Phospho-GSK3 beta (Ser9) Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of 293 cells using Phospho-GSK3 beta (Ser9) Polyclonal Antibody at dilution of 1:1000

Phospho-GSK3beta (S9) Polyclonal Antibody

Research Use Only
E-AB-20886
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    Phospho-GSK3beta (S9) Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    WB,IHC,IP,ELISA
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Scientific Description
    Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Phosphorylates MACF1 and this phosphorylation inhibits the binding of MACF1 to microtubules which is critical for its role in bulge stem cell migration and skin wound repair.
  • UNSPSC
    12352203