Immunohistochemical analysis of paraffin-embedded human brain tissue using ILK (Phospho-Ser246) antibody (left)or the same antibody preincubated with blocking peptide (right).
Immunohistochemical analysis of paraffin-embedded human brain tissue using ILK (Phospho-Ser246) antibody (left)or the same antibody preincubated with blocking peptide (right).
Phospho-ILK (Ser246) Antibody
CSB-PA059405
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetILK
Overview
- SupplierCusabio
- Product NamePhospho-ILK (Ser246) Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3611
- Target nameILK
- Target descriptionintegrin linked kinase
- Target synonyms59 kDa serine/threonine-protein kinase; beta-integrin-linked kinase; epididymis secretory protein Li 28; HEL-S-28; ILK-1; ILK-2; integrin-linked kinase-2; integrin-linked protein kinase; P59; p59ILK
- HostRabbit
- IsotypeIgG
- Protein IDQ13418
- Protein NameIntegrin-linked protein kinase
- Scientific DescriptionTransduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Hannigan G.E., Nature 379:91-96(1996). Janji B., Oncogene 19:3069-3077(2000). Tadic B., Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203