Western Blot Positive WB detected in:Jurkat whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate(treated with EGF or Pervanadate) All lanes: Phospho-LAT antibody at 2.9microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38 KDa Observed band size: 38 KDa
Western Blot Positive WB detected in:Jurkat whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate(treated with EGF or Pervanadate) All lanes: Phospho-LAT antibody at 2.9microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38 KDa Observed band size: 38 KDa
Phospho-LAT (Y191) Recombinant Monoclonal Antibody
CSB-RA012767A191PHHU
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetLAT
Overview
- SupplierCusabio
- Product NamePhospho-LAT (Y191) Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2E4
- ConjugateUnconjugated
- Gene ID27040
- Target nameLAT
- Target descriptionlinker for activation of T cells
- Target synonyms36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; IMD52; LAT1; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells family member 1; p36-38; pp36
- IsotypeIgG
- Protein IDO43561
- Protein NameLinker for activation of T-cells family member 1
- Scientific DescriptionRequired for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203