Western blot analysis of extracts from Jurkat cells treated with serum using MAP2K3 (Phospho-Thr222) Antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-MAP2K3 (Thr222) Antibody
CSB-PA597904
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMAP2K3
Overview
- SupplierCusabio
- Product NamePhospho-MAP2K3 (Thr222) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5606
- Target nameMAP2K3
- Target descriptionmitogen-activated protein kinase kinase 3
- Target synonymsdual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPK/ERK kinase 3; MAPKK 3; MAPKK3; MEK 3; MEK3; MKK3; PRKMK3; SAPK kinase 2; SAPKK2; SAPKK-2; stress-activated protein kinase kinase 2
- HostRabbit
- IsotypeIgG
- Protein IDP46734
- Protein NameDual specificity mitogen-activated protein kinase kinase 3
- Scientific DescriptionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. Derijard B., Science 267:682-685(1995). Moriguchi T., J. Biol. Chem. 271:26981-26988(1996). The MGC Project Team; Genome Res. 14:2121-2127(2004).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203