Western blot analysis of extracts from HT29 cells untreated or treated with UV using P38 MAPK(Phospho-Thr180) Antibody.
Phospho-MAPK14 (Thr180) Antibody
CSB-PA175647
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMAPK14
Overview
- SupplierCusabio
- Product NamePhospho-MAPK14 (Thr180) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1432
- Target nameMAPK14
- Target descriptionmitogen-activated protein kinase 14
- Target synonymsCSAID-binding protein; CSBP; CSBP1; CSBP2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; EXIP; MAP kinase 14; MAP kinase Mxi2; MAP kinase p38 alpha; MAX-interacting protein 2; mitogen-activated protein kinase 14; mitogen-activated protein kinase p38 alpha; Mxi2; p38; p38 MAP kinase; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK2A; stress-activated protein kinase 2A
- HostRabbit
- IsotypeIgG
- Protein IDQ16539
- Protein NameMitogen-activated protein kinase 14
- Scientific DescriptionResponds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. Kim JE, et al. (2005) J Proteome Res Jul-Aug; 4(4): 1339-1346 Meng F, et al. (2005) Am J Physiol Cell Physiol May 25 Jin ZH, et al. (2005)Oncogene Mar 17; 24(12): 1973-1981
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203