Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEF2A(Phospho-Thr312) Antibody(left) or the same antibody preincubated with blocking peptide(right).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEF2A(Phospho-Thr312) Antibody(left) or the same antibody preincubated with blocking peptide(right).
Phospho-MEF2A (Thr312) Antibody
CSB-PA024919
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMEF2A
Overview
- SupplierCusabio
- Product NamePhospho-MEF2A (Thr312) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4205
- Target nameMEF2A
- Target descriptionmyocyte enhancer factor 2A
- Target synonymsADCAD1; MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A); mef2; myocyte-specific enhancer factor 2A; RSRFC4; RSRFC9; serum response factor-like protein 1
- HostRabbit
- IsotypeIgG
- Protein IDQ02078
- Protein NameMyocyte-specific enhancer factor 2A
- Scientific DescriptionThe process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes agamous and deficiens and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain K Satoh, J Ohnishi, A Sato, et al. (2007) Nemo-Like Kinase-Myocyte Enhancer Factor 2A Signaling Regulates Anterior Formation in Xenopus Development. Molecular and Cellular Biology, 27(21):7623-30. This article references the use of the #11039 in the following applications :Western blotting
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203