
Western blot analysis of extracts from Rat and Mouse brain tissue using TrkA(Phospho-Ser791) Antibody.
Phospho-NTRK1 (Ser791) Antibody
CSB-PA198739
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetNTRK1
Overview
- SupplierCusabio
- Product NamePhospho-NTRK1 (Ser791) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4914
- Target nameNTRK1
- Target descriptionneurotrophic receptor tyrosine kinase 1
- Target synonymsgp140trk; high affinity nerve growth factor receptor; MTC; neurotrophic tyrosine kinase, receptor, type 1; Oncogene TRK; p140-TrkA; TRK; TRK1; TRK1-transforming tyrosine kinase protein; TRKA; Trk-A; tropomyosin-related kinase A; tyrosine kinase receptor A
- HostRabbit
- IsotypeIgG
- Protein IDP04629
- Protein NameHigh affinity nerve growth factor receptor
- Scientific DescriptionRequired for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway. Wiese S, et al. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):17210-5. Valdez G, et al. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12270-5 Inoue K, et al. J Biol Chem. 2007 Aug 17;282(33):24175-84
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203