Western blot analysis of extracts from LOVO cells treated with starved using PAK1/2 (Phospho-Ser199) Antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from LOVO cells treated with starved using PAK1/2 (Phospho-Ser199) Antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-PAK1 (Ser199) Antibody
CSB-PA199192
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPAK1
Overview
- SupplierCusabio
- Product NamePhospho-PAK1 (Ser199) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5058
- Target namePAK1
- Target descriptionp21 (RAC1) activated kinase 1
- Target synonymsalpha-PAK; IDDMSSD; p21 protein (Cdc42/Rac)-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p65-PAK; PAKalpha; serine/threonine-protein kinase PAK 1; STE20 homolog, yeast
- HostRabbit
- IsotypeIgG
- Protein IDQ13153
- Protein NameSerine/threonine-protein kinase PAK 1
- Scientific DescriptionThe activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. Brown J.L., Curr. Biol. 6:598-605(1996). Sells M.A., Curr. Biol. 7:202-210(1997). The MGC Project Team; Genome Res. 14:2121-2127(2004).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203