Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using PAK2 (Phospho-Ser197) antibody (left)or the same antibody preincubated with blocking peptide (right).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using PAK2 (Phospho-Ser197) antibody (left)or the same antibody preincubated with blocking peptide (right).
Phospho-PAK2 (Ser197) Antibody
CSB-PA149930
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPAK2
Overview
- SupplierCusabio
- Product NamePhospho-PAK2 (Ser197) Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5062
- Target namePAK2
- Target descriptionp21 (RAC1) activated kinase 2
- Target synonymsgamma-PAK; p21 (CDKN1A)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; p58; PAK-2; PAK65; PAKgamma; S6/H4 kinase; serine/threonine-protein kinase PAK 2
- HostRabbit
- IsotypeIgG
- Protein IDQ13177
- Protein NameSerine/threonine-protein kinase PAK 2
- Scientific DescriptionThe activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. Martin G.A., EMBO J. 14:1970-1978(1995). The MGC Project Team; Genome Res. 14:2121-2127(2004). Olsen J.V., Cell 127:635-648(2006).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203