Western blot analysis of extracts from HeLa cells treated with Heatshock using Phospho-PKCB (Ser661) antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HeLa cells treated with Heatshock using Phospho-PKCB (Ser661) antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-PRKCB (Ser661) Antibody
CSB-PA067031
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetPRKCB
Overview
- SupplierCusabio
- Product NamePhospho-PRKCB (Ser661) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5579
- Target namePRKCB
- Target descriptionprotein kinase C beta
- Target synonymsPKCB; PKC-B; PKCbeta; PKC-beta; PKCI(2); PRKCB1; PRKCB2; protein kinase C beta type; protein kinase C, beta 1 polypeptide
- HostRabbit
- IsotypeIgG
- Protein IDP05771
- Protein NameProtein kinase C beta type
- Scientific DescriptionCalcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. Zhu M, Chen J, Jiang H, Miao C (2013) Cardiovasc Diabetol 12, 13 Leonard TA, et al. (2011) Cell 144, 55-66 Qiao M, et al. (2010) Mol Cell 38, 512-23
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203