
Western blot analysis of extracts from 293 cells untreated or treated with PMA using PKCth(Phospho-Ser695) Antibody.
Phospho-PRKCQ (Ser695) Antibody
CSB-PA160849
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPRKCQ
Overview
- SupplierCusabio
- Product NamePhospho-PRKCQ (Ser695) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5588
- Target namePRKCQ
- Target descriptionprotein kinase C theta
- Target synonymsnPKC-theta; PRKCT; protein kinase C theta type
- HostRabbit
- IsotypeIgG
- Protein IDQ04759
- Protein NameProtein kinase C theta type
- Scientific DescriptionThis is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Xu ZB, et al.(2004) J Biol Chem 279:50401-50409 Thebault S, et al. (2004) Mol Immunol 40: 931-942
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203