
Western blot analysis of extracts from 3T3 cells treated with PMA using Phospho-FAK (Ser843) antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-PTK2 (Ser843) Antibody
CSB-PA442752
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPTK2
Overview
- SupplierCusabio
- Product NamePhospho-PTK2 (Ser843) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5747
- Target namePTK2
- Target descriptionprotein tyrosine kinase 2
- Target synonymsFADK; FADK 1; FAK; FAK1; FAK-related non-kinase polypeptide; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; p125FAK; pp125FAK; PPP1R71; protein phosphatase 1 regulatory subunit 71; PTK2 protein tyrosine kinase 2
- HostRabbit
- IsotypeIgG
- Protein IDQ05397
- Protein NameFocal adhesion kinase 1
- Scientific DescriptionNon-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. Jiang X, Sinnett-Smith J, Rozengurt E (2007)Cell Signal 19, 1000-10 . Jacamo R, Jiang X, Lunn JA, Rozengurt E (2007)J Cell Physiol 210, 436-44. Le Boeuf F, Houle F, Sussman M, Huot J (2006)Mol Biol Cell 17, 3508-20 .
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203