Western blot analysis of extracts from NIH-3T3 cells treated with EGF using MSK1 (Phospho-Ser212) antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-RPS6KA5 (Ser212) Antibody
CSB-PA997224
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetRPS6KA5
Overview
- SupplierCusabio
- Product NamePhospho-RPS6KA5 (Ser212) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9252
- Target nameRPS6KA5
- Target descriptionribosomal protein S6 kinase A5
- Target synonyms90 kDa ribosomal protein S6 kinase 5; MSK1; MSPK1; nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; RLPK; RSKL; RSK-like protein kinase; S6K-alpha-5
- HostRabbit
- IsotypeIgG
- Protein IDO75582
- Protein NameRibosomal protein S6 kinase alpha-5
- Scientific DescriptionSerine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of Ser-1 of histone H2A. Phosphorylates Ser-10 of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate Ser-28 of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14). McCoy CE, et al. (2007) Biochem J 402, 491-501 McCoy CE, et al. (2005)Biochem J 387, 507-17
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203