Western Blot Positive WB detected in Hela whole cell lysate,A549 whole cell lysate All lanes Phospho-SMAD2 antibody at 1.07microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 58 KDa Observed band size: 58 KDa
Western Blot Positive WB detected in Hela whole cell lysate,A549 whole cell lysate All lanes Phospho-SMAD2 antibody at 1.07microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 58 KDa Observed band size: 58 KDa
Phospho-SMAD2 (S250) Recombinant Monoclonal Antibody
CSB-RA618017A250PHHU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetSMAD2
Overview
- SupplierCusabio
- Product NamePhospho-SMAD2 (S250) Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4D12
- ConjugateUnconjugated
- Gene ID4087
- Target nameSMAD2
- Target descriptionSMAD family member 2
- Target synonymshMAD-2; hSMAD2; JV18; JV18-1; MAD homolog 2; MADH2; MADR2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Sma- and Mad-related protein 2; SMAD, mothers against DPP homolog 2
- IsotypeIgG
- Protein IDQ15796
- Protein NameMothers against decapentaplegic homolog 2
- Scientific DescriptionReceptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203