Western blot analysis of extracts from 3T3 cells treated with starvation using SP1(Phospho-Thr739) Antibody.
Western blot analysis of extracts from 3T3 cells treated with starvation using SP1(Phospho-Thr739) Antibody.
Phospho-SP1 (Thr739) Antibody
CSB-PA730012
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Rat
TargetSP1
Overview
- SupplierCusabio
- Product NamePhospho-SP1 (Thr739) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6667
- Target nameSP1
- Target descriptionSp1 transcription factor
- Target synonymsspecificity protein 1; transcription factor Sp1
- HostRabbit
- IsotypeIgG
- Protein IDP08047
- Protein NameTranscription factor Sp1
- Scientific DescriptionTranscription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-a G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. Thiesen HJ,et al.(1990)Nucleic Acids Res.18(11):3203-9. Zutter MM,et al.(1997) Blood.90(2):678-89. Lou Z,et al.(2005)Cancer Res.65(3):1007-17
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203