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Phospho-STAT6(Y641) Polyclonal Antibody

RD268151A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetSTAT6
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    Phospho-STAT6(Y641) Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6778
  • Target name
    STAT6
  • Target description
    signal transducer and activator of transcription 6
  • Target synonyms
    D12S1644; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; STAT, interleukin4-induced; STAT6B; STAT6C; transcription factor IL-4 STAT
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203