Western blot analysis of extracts from HepG2 cells treated with EGF using ACK1 (Phospho-Tyr284) Antibody.The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HepG2 cells treated with EGF using ACK1 (Phospho-Tyr284) Antibody.The lane on the right is treated with the antigen-specific peptide.
Phospho-TNK2 (Tyr284) Antibody
CSB-PA309705
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetTNK2
Overview
- SupplierCusabio
- Product NamePhospho-TNK2 (Tyr284) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10188
- Target nameTNK2
- Target descriptiontyrosine kinase non receptor 2
- Target synonymsACK; ACK1; ACK-1; activated CDC42 kinase 1; activated Cdc42-associated kinase 1; activated p21cdc42Hs kinase; p21cdc42Hs; tyrosine kinase non-receptor protein 2
- HostRabbit
- IsotypeIgG
- Protein IDQ07912
- Protein NameActivated CDC42 kinase 1
- Scientific DescriptionNon-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes. Manser E., Nature 363:364-367(1993). Ota T., Nat. Genet. 36:40-45(2004). Eisenmann K.M., Nat. Cell Biol. 1:507-513(1999)
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203