Western blot analysis of extracts from Hela cells using p53(Phospho-Ser315) Antibody(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
Western blot analysis of extracts from Hela cells using p53(Phospho-Ser315) Antibody(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
Phospho-TP53 (Ser315) Antibody
CSB-PA826876
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTP53
Overview
- SupplierCusabio
- Product NamePhospho-TP53 (Ser315) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7157
- Target nameTP53
- Target descriptiontumor protein p53
- Target synonymsantigen NY-CO-13; BCC7; BMFS5; cellular tumor antigen p53; LFS1; mutant tumor protein 53; P53; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; TRP53; tumor protein 53; tumor supressor p53
- HostRabbit
- IsotypeIgG
- Protein IDP04637
- Protein NameCellular tumor antigen p53
- Scientific DescriptionActs as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Lu, H. et al. (1997) Mol. Cell. Biol. 17, 5923-5934. Lohrum, M. et.al. (1996) Oncogene 13, 2527-2539. Posp
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203