Western blot analysis of extracts from HT29 cells untreated(lane 1) or treated with Anisomycin(lane 2) using TYK2(Phospho-Tyr1054) Antibody.
Western blot analysis of extracts from HT29 cells untreated(lane 1) or treated with Anisomycin(lane 2) using TYK2(Phospho-Tyr1054) Antibody.
Phospho-TYK2 (Tyr1054) Antibody
CSB-PA154201
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTYK2
Overview
- SupplierCusabio
- Product NamePhospho-TYK2 (Tyr1054) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7297
- Target nameTYK2
- Target descriptiontyrosine kinase 2
- Target synonymsIMD35; JTK1; non-receptor tyrosine-protein kinase TYK2
- HostRabbit
- IsotypeIgG
- Protein IDP29597
- Protein NameNon-receptor tyrosine-protein kinase TYK2
- Scientific DescriptionTYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730. Gauzzi MC, et al. (1996) J Biol Chem. 271(34): 20494-20500.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203