Phosphotyrosine antibody [PY20] (Biotin)
GTX16388
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityOther Species
Overview
- SupplierGeneTex
- Product NamePhosphotyrosine antibody [PY20] (Biotin)
- Delivery Days Customer9
- Antibody SpecificityClone PY20 specifically recognizes phosphorylated tyrosine residues and does not react with phosphorylated threonine or serine residues.
- Application Supplier NoteELISA: 1/5000. ICC: 1/500. WB: 1/5000. IHC: 1/500. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPY20
- Concentration1 mg/ml
- ConjugateBiotin
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionThe role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research.
- ReactivityOther Species
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Extracellular-signal regulated kinase 8 of Trypanosoma brucei uniquely phosphorylates its proliferating cell nuclear antigen homolog and reveals exploitable properties. Valenciano AL et al., 2016 Oct 17, Cell CycleRead more
- OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. Wang TH et al., 2016 Apr, Mol CarcinogRead more