PHT-7.3

MedChem Express

PHT-7.3 [1614225-93-2]

5

1614225-93-2

Research Use Only

99.29

C24H23N3O3S

433.52

PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4.7 microM). PHT-7.3 inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling. PHT-7.3 has antitumor activity[1].

O=C1C2=C(C=CC=C2)C(CC3OCCCO3)=NN1CC4=NC(C5=CC=C(C)C=C5)=CS4

-20°C,2°C to 8°C

12352200