Phthalimide-PEG4-PDM-OTBS

TargetMol Chemicals

Phthalimide-PEG4-PDM-OTBS

999

Chemical

Research Use Only

Phthalimide-PEG4-PDM-OTBS

C27H44N2O7Si

536.73

Phthalimide-PEG4-PDM-OTBS is a PROTAC linker comprised of polyethylene glycols (PEGs) utilized in the synthesis of various PROTACs, which consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein, leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1].

3 years

O=C(N1CCOCCOCCOCCO[C@@H]2C[C@@H](CO[Si](C(C)(C)C)(C)C)NC2)C3=C(C=CC=C3)C1=O

-20°C

12352200