Physalin A
TN4774
CAS Number23027-91-0
Product group Chemicals
Molecular Weight526.538
Overview
- SupplierTargetMol Chemicals
- Product NamePhysalin A
- Delivery Days Customer1001
- CAS Number23027-91-0
- Category SupplierChemical
- Chemical NamePhysalin A
- Molecular FormulaC28H30O10
- Molecular Weight526.538
- Scientific DescriptionPhysalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor expression. Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells.
- Shelf life instruction3 years
- SMILES[H][C@@]12C(=O)[C@]3(O)O[C@]11[C@@](C)(OC(=O)[C@@]1(O)CC[C@@]1([H])[C@@]3([H])[C@H](O)C=C3CC=CC(=O)[C@]13C)[C@H]1C[C@]2(C)C(=C)C(=O)O1
- Storage Instruction-20°
- UNSPSC12352200