Physalin H

MedChem Express

Physalin H

10

Research Use Only

C28H31ClO10

562.99

Physalin H is a natural product that can be isolated from Solanum nigrum . Physalin H is an inhibitor of Hedgehog ( Hh ) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC 50 value of 0.7 microM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC 50 values of 5.7 and 6.8 microM, respectively [1] .

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