PI3K-IN-35

TargetMol Chemicals

PI3K-IN-35

107

2458163-99-8

Chemical

PI3K-IN-35

C25H23N7O2

453.5

PI3K-IN-35 (Compound 6l) is a highly selective inhibitor of PI3K, acting on PI3K-alfa (IC50: 13.98 uM), PI3K-bèta (IC50: 7.22 uM) and PI3K-delta (IC50: 10.94 uM). PI3K-IN-35 blocks the cell cycle in G2/M phase and induces apoptosis. PI3K-IN-35 can be used to study leukaemia.

3 years

C(#N)C=1C(=NC(NN=CC=2C=3C(NC2)=CC=CC3)=NC1N4CCOCC4)C5=CC=C(OC)C=C5

-20°

12352200