PI3K-IN-47
ORB2278356
Estimated Purity98.00%
Product group Chemicals
Molecular Weight1027.07
Overview
- SupplierBiorbyt
- Product NamePI3K-IN-47
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity98.00%
- Molecular FormulaC50H46F4N8O8S2
- Molecular Weight1027.07
- Scientific DescriptionPI3K-IN-47 (Compound 27) is a potent bivalent inhibitor targeting the phosphoinositide 3-kinases (PI3K) family, with IC50 values of 0.44 nM for PI3Kalpha, and 7.18 nM, 13.92 nM, and 22.83 nM for PI3Kbeta, PI3Kgamma, and PI3Kdelta respectively. It induces G1 phase cell cycle arrest and exhibits anti-neoplastic properties by restraining colony formation and cell migration. Additionally, PI3K-IN-47 has demonstrated the ability to suppress tumor growth in HGC-27 xenograft mouse models [1].
- Storage Instruction-20°C
- UNSPSC12352200