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PI3K/Akt/mTOR-IN-2

T60564
TargetMol Chemicals
CAS Number2757804-89-8
Product group Chemicals
Molecular Weight285.29
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PI3K/Akt/mTOR-IN-2
  • Delivery Days Customer
    9
  • CAS Number
    2757804-89-8
  • Category Supplier
    Chemical
  • Chemical Name
    PI3K/Akt/mTOR-IN-2
  • Molecular Formula
    C17H13F2NO
  • Molecular Weight
    285.29
  • Scientific Description
    PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor.PI3K/Akt/mTOR-IN-2 has anticancer effects and is selective for MDA-MB-231 cells with an IC50 of 2.29 uM.PI3K/Akt/mTOR-IN-2 exhibits anticancer activity and induces cycle arrest and apoptosis in cancer cells. PI3K/Akt/mTOR-IN-2 has anticancer activity and can induce cycle arrest and apoptosis in cancer cells.
  • Shelf life instruction
    3 years
  • SMILES
    FC=1C=C(C2C3=C(C=4C(N3)=CC=CC4)CCO2)C=C(F)C1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Qin J, et al. Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway. Bioorg Med Chem. 2021 Dec 31;55:116594.