PI3K/Akt/mTOR-IN-3

MedChem Express

PI3K/Akt/mTOR-IN-3

10

Research Use Only

C34H51NO2

505.77

PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57microM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 microM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest[1].

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