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PIAS1 antibody

Research Use Only
ORB66686
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse
TargetPias1
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Overview

  • Supplier
    Biorbyt
  • Product Name
    PIAS1 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Conjugate
    Unconjugated
  • Gene ID56469
  • Target name
    Pias1
  • Target description
    protein inhibitor of activated STAT 1
  • Target synonyms
    2900068C24Rik; Ddxbp; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; GB; GBP; protein inhibitor of activated STAT protein 1; RING-type E3 ubiquitin transferase PIAS1
  • Host
    Mouse
  • Protein IDO88907
  • Protein Name
    E3 SUMO-protein ligase PIAS1
  • Scientific Description
    Mouse monoclonal to PIAS1.PIAS1 is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator oftranscription)] family of transcriptional modulators. PIAS1 functions as an E3 small ubiquitin-likemodifier (SUMO) ligase. It stabilizes the interaction between UBE2I and the substrate, and functionsas a SUMO-tethering factor. PIAS1 plays an important role in the transcriptional regulation ofnumerous cellular pathways, including STAT, NF-B, p53 and the steroid hormone signalingpathways. Recent studies revealed that PIAS1 is an important regulator for innate immunity,inflammatory cytokine signaling and regulatory T cell differentiation.
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203