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Piceatannol [10083-24-6]

Research Use Only
P3209
LKT Laboratories
Estimated Purity≥99%
Product group Chemicals
€ 296,00
25 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Piceatannol [10083-24-6]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥99%
  • Format
    DMSO (20mg/ml), Ethanol (10mg/ml)
  • Scientific Description
    Polyphenolic hydroxystilbene, resveratrol derivative; HPH-2 inhibitor, potential PI3K and JAK1 inhibitor.
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Yum S, Doh HJ, Hong S, et al. Piceatannol, a hydroxystilbene natural product, stabilizes HIF-1alfa protein by inhibiting HIF prolyl hydroxylase. Eur J Pharmacol. 2013 Jan 15;699(1-3):124-31. PMID: 23261967. Jayasooriya RG, Lee YG, Kang CH, et al. Piceatannol inhibits MMP-9-dependent invasion of tumor necrosis factor-alfa-stimulated DU145 cells by suppressing the Akt-mediated nuclear factor-kappaB pathway. Oncol Lett. 2013 Jan;5(1):341-347. PMID: 23255946. Li Z, Yang X, Dong S, et al. DNA breakage induced by piceatannol and copper(II): Mechanism and anticancer properties. Oncol Lett. 2012 May;3(5):1087-1094. PMID: 22783397. Kwon JY, Seo SG, Heo YS, et al. Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation. J Biol Chem. 2012 Mar 30;287(14):11566-78. PMID: 22298784. Kwon GT, Jung JI, Song HR, et al. Piceatannol inhibits migration and invasion of prostate cancer cells: possible mediation by decreased interleukin-6 signaling. J Nutr Biochem. 2012 Mar;23(3):228-38. PMID: 21497499. Lee YM, Lim do Y, Cho HJ, et al. Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity. Cancer Lett. 2009 Nov 28;285(2):166-73. PMID: 19487074. Rossi M, Caruso F, Opazo C, et al. Crystal and molecular structure of piceatannol; scavenging features of resveratrol and piceatannol on hydroxyl and peroxyl radicals and docking with transthyretin. J Agric Food Chem. 2008 Nov 26;56(22):10557-66. PMID: 18959413. Kim HJ, Lee KW, Kim MS, et al. Piceatannol attenuates hydrogen-peroxide- and peroxynitrite-induced apoptosis of PC12 cells by blocking down-regulation of Bcl-XL and activation of JNK. J Nutr Biochem. 2008 Jul;19(7):459-66. PMID: 17869087.