Picrotoxinin (Standard)

MedChem Express

Picrotoxinin (Standard) [17617-45-7]

999

17617-45-7

Research Use Only

C15H16O6

292.28

Picrotoxinin (Standard) is the analytical standard of Picrotoxinin. This product is intended for research and analytical applications. Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. Picrotoxinin inhibits alpha1beta2gamma2L GABAA receptor with an IC50 of 1.15 microM[1].

O=C1[C@]([C@@H]2C(C)=C)([H])[C@]3(O)C[C@]4([H])[C@](O4)(C(O5)=O)[C@]3(C)[C@@]5([H])[C@]2([H])O1

12352200