PIDD antibody

Biorbyt

PIDD antibody

16

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human PIDD.

Western Blot

WB:1:1000-1:3000 WB

Research Use Only

Polyclonal

100 ug/ml

Unconjugated

PIDD1

p53-induced death domain protein 1

leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; LRDD; p53-induced death domain-containing protein 1; p53-induced protein with a death domain; PIDD

Rabbit

p53-induced death domain-containing protein 1

Rabbit polyclonal to PIDD. P53-induced protein with a death domain (PIDD ) promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. PIDD associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. PIDD also associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which is an important regulator in apoptotic pathway.

Human, Mouse

-20°C

12352203