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PIG3 Protein, Human, Recombinant (His)

PIG3 Protein, Human, Recombinant (His)

TMPY-01561
TargetMol Chemicals
Molecular Weight37.8 kDa (predicted); 37.5 kDa (reducing conditions)
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PIG3 Protein, Human, Recombinant (His)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Molecular Weight
    37.8 kDa (predicted); 37.5 kDa (reducing conditions)
  • Scientific Description
    Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of Nutlin-3.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200