PIK5-12d

MedChem Express

PIK5-12d

14

Research Use Only

99.90

C52H64N10O7S

973.19

PIK5-12d is a PROTAC PIKfyve degrader ( DC 50 : 1.48 nM). PIK5-12d induces massive cytoplasmic vacuolization and blocks autophagic flux in multiple prostate cancer cells. PIK5-12d inhibits prostate cancer cell proliferation. PIK5-12d has anti-tumor activity [1] .

CC1=CC=CC(/C=N/NC2=NC(OCCC3=CC=C(NC(CCCCC(N[C@H](C(N4[C@@H](C[C@H](C4)O)C(NCC5=CC=C(C=C5)C6=C(N=CS6)C)=O)=O)C(C)(C)C)=O)=O)C=C3)=NC(N7CCOCC7)=C2)=C1

-20°C,2°C to 8°C

12352200