Bio-Connect
CgoaEGY7MamEdweXAAAAAGsm5ng806.png
CgoaEGY7MamEdweXAAAAAGsm5ng806.png
CgoaEGY7MamEdweXAAAAAGsm5ng806.png

PIM1-IN-1 [1417630-95-5]

Research Use Only
T12474
TargetMol Chemicals
CAS Number1417630-95-5
Product group Chemicals
Molecular Weight474.56
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PIM1-IN-1 [1417630-95-5]
  • Delivery Days Customer
    86
  • CAS Number
    1417630-95-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PIM1-IN-1
  • Molecular Formula
    C25H30N8O2
  • Molecular Weight
    474.56
  • Scientific Description
    PIM1-IN-1 is a potent and highly selective inhibitor of PIM1/3 (IC50s: 7 nM for PIM1, 5530 nM for PIM2, and 70 nM for PIM3) with antiproliferative and anti-cancer activity.
  • Shelf life instruction
    3 years
  • SMILES
    COCCN1CCOc2c1cnn1c(nnc21)-c1ccc2cccc(NCC3CCNCC3)c2n1
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Martínez-González S, et al. Discovery of novel triazolo[4,3-b]pyridazin-3-yl-quinoline derivatives as PIM inhibitors. Eur J Med Chem. 2019 Feb 19;168:87-109.
    Read more