PIM1 / Pim-1 Antibody (aa282-312)

LifeSpan BioSciences

PIM1 / Pim-1 Antibody (aa282-312)

23

Human PIM1 / Pim-1

Proto-oncogene serine/threonine-protein kinase PIM-1 is an enzyme that in humans is encoded by the PIM1 gene. It is mapped to 6p21.2. Primarily expressed in spleen, thymus, bone marrow, prostate, oral epithelial, hippocampus and fetal liver cells, It has also been found to be highly expressed in cell cultures isolated from human tumors. PIM-1 is mainly involved in cell cycle progression, apoptosis and transcriptional activation, as well as more general signal transduction pathways. It has been found a physiologic role of the PIM-1 oncogene during hematopoietic development and a deregulation of the gene in various leukemias. It also has a role in cardioprotection downstream of AKT activation.. WB (0.5 - 1 µg/ml) Proto-oncogene serine/threonine-protein kinase PIM-1 is an enzyme that in humans is encoded by the PIM1 gene. It is mapped to 6p21.2. Primarily expressed in spleen, thymus, bone marrow, prostate, oral epithelial, hippocampus and fetal liver cells, It has also been found to be highly expressed in cell cultures isolated from human tumors. PIM-1 is mainly involved in cell cycle progression, apoptosis and transcriptional activation, as well as more general signal transduction pathways. It has been found a physiologic role of the PIM-1 oncogene during hematopoietic development and a deregulation of the gene in various leukemias. It also has a role in cardioprotection downstream of AKT activation.

Western Blot

Research Use Only

Polyclonal

Unconjugated

...

PIM1

Pim-1 proto-oncogene, serine/threonine kinase

Oncogene PIM1; PIM; pim-1 oncogene (proviral integration site 1); proto-oncogene serine/threonine-protein kinase pim-1; serine/threonine-protein kinase pim-1

Rabbit

IgG

Bovine, Canine, Equine, Human, Porcine, Rabbit, Sheep

-20°C,2°C to 8°C

12352203