Western Blot Positive WB detected in: Mouse stomach tissue All lanes: PIM3 antibody at 3.4ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 36 kDa Observed band size: 36 kDa
Western Blot Positive WB detected in: Mouse stomach tissue All lanes: PIM3 antibody at 3.4ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 36 kDa Observed band size: 36 kDa
PIM3 Antibody
CSB-PA771444LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPIM3
Overview
- SupplierCusabio
- Product NamePIM3 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID415116
- Target namePIM3
- Target descriptionPim-3 proto-oncogene, serine/threonine kinase
- Target synonymspim-3; pim-3 oncogene; serine/threonine kinase Pim-3; serine/threonine-protein kinase pim-3
- HostRabbit
- IsotypeIgG
- Protein IDQ86V86
- Protein NameSerine/threonine-protein kinase pim-3
- Scientific DescriptionProto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203