Bio-Connect

PIN1 Polyclonal Antibody

RD81553A
Reddot Biotech
TargetPIN1
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PIN1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Concentration
    1 mg/ml
  • Gene ID5300
  • Target name
    PIN1
  • Target description
    peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • Target synonyms
    DOD; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; PPIase Pin1; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein interacting with never in mitosis A1; rotamase Pin1; UBL5
  • Scientific Description
    Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimers disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203