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PIP4K-IN-a131 [2055405-95-1]

PIP4K-IN-a131 [2055405-95-1]

T39452
TargetMol Chemicals
CAS Number2055405-95-1
DownloadMSDS
Product group Chemicals
Molecular Weight295.345
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PIP4K-IN-a131 [2055405-95-1]
  • Delivery Days Customer
    14
  • CAS Number
    2055405-95-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PIP4K-IN-a131
  • Molecular Formula
    C20H13N3
  • Molecular Weight
    295.345
  • Scientific Description
    PIP4K-IN-a131 is a selective inhibitor of PIP4K lipid kinases, demonstrating IC50 values of 1.9 microM for PIP4K2A and 0.6 microM for PIP4Ks. It exhibits cancer-selective lethality by simultaneously blocking the lipid kinase PIP4Ks and mitotic pathways.
  • Shelf life instruction
    3 years
  • SMILES
    N#C\C(=C/c1cccc2cnccc12)c1c[nH]c2ccccc12
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality. Kitagawa M et al., 2017 Dec 19, Nat Commun
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