PKC-IN-1

MedChem Express

PKC-IN-1 [1046787-18-1]

10

1046787-18-1

Research Use Only

99.79

C25H37FN8O2

500.61

PKC-IN-1 is a potent, ATP-competitive and reversible inhibitor of conventional PKC enzymes with K i s of 5.3 and 10.4 nM for human PKCbeta and PKCalpha, and IC 50 s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM for PKCalpha, PKCbetaI, PKCbetaII, PKCtheta, PKCgamma, PKC mu and PKCepsilon, respectively.

O=C(N1[C@@H](C)CN(CC2CCOCC2)[C@H](C)C1)N(C3)C(C)(C)C4=C3C(NC5=NC(C)=NC=C5F)=NN4

-20°C,2°C to 8°C

12352200