PKC-IN-1 [1046787-18-1]

MedChem Express

PKC-IN-1 [1046787-18-1]

10

1046787-18-1

Research Use Only

98.79

C25H37FN8O2

500.61

PKC-IN-1 is a potent, ATP-competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5.3 and 10.4 nM for human PKCbeta and PKCalpha, and IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM for PKCalpha, PKCbetaI, PKCbetaII, PKCtheta, PKCgamma, PKC mu and PKCepsilon, respectively.

O=C(N1[C@@H](C)CN(CC2CCOCC2)[C@H](C)C1)N(C3)C(C)(C)C4=C3C(NC5=NC(C)=NC=C5F)=NN4

-20°C,2°C to 8°C

12352200