PKC-theta inhibitor 1

MedChem Express

PKC-theta inhibitor 1 [1160501-81-4]

10

1160501-81-4

Research Use Only

99.73

C17H15F3N4O

348.32

PKC-theta inhibitor 1 is the PKCtheta inhibitor with an Ki value of 6 nM, inhibits IL-2 production in vivo with an IC50 of 0.19 microM. PKC-theta inhibitor 1 demonstrates a reduction of symptoms in a mouse model of multiple sclerosis[1].

NCC1(C2=CC=CC(C3=C4C(NN=C4C(F)(F)F)=NC=C3)=C2)COC1

-20°C,2°C to 8°C

12352200