PKI-402 [1173204-81-3]
P4132
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NamePKI-402 [1173204-81-3]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatDMSO 0.4 mg/mL (0.7 mM); Water Insoluble; Ethanol Insoluble
- Scientific Descriptionp110alfa PI3K and mTOR inhibitor.
- Storage Instruction-20°C
- UNSPSC12352200
References
- Mallon R, Hollander I, Feldberg L, et al. Antitumor efficacy profile of PKI-402, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor. Mol Cancer Ther. 2010 Apr;9(4):976-84. PMID: 20371716. Dehnhardt CM, Venkatesan AM, Delos Santos E, et al. Lead optimization of N-3-substituted 7-morpholinotriazolopyrimidines as dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors: discovery of PKI-402. J Med Chem. 2010 Jan 28;53(2):798-810. PMID: 19968288.