Western Blot analysis of 231 cell using PLAT Polyclonal Antibody at dilution of 1:450
PLAT Polyclonal Antibody
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E-AB-12879
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePLAT Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.4mg/ml
- Scientific DescriptionThis gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
- UNSPSC12352203