Plogosertib

MedChem Express

Plogosertib

10

Research Use Only

99.95

C34H48N8O3

616.80

Plogosertib (CYC140) is a selective, potent, and orally active ATP-competitive PLK1 inhibitor ( IC 50 : 3 nM). Plogosertib is an anti-cancer agent with anti-proliferative activity. Plogosertib can be used in the research of several tumors, including esophageal, gastric, leukemia, non-small cell lung cancer, ovarian, and squamous cell cancers [1] [2] .

O=C1C2(CC2)CN(C3CCCC3)C4=NC(NC5=C(C=C(C=C5)C(N[C@@H]6CC[C@@H](N7CCN(CC7)C)CC6)=O)OC)=NC=C4N1C

2°C to 8°C

12352200